Here is a quick workaround to resolve this issue. Some users are faced with a strange issue where the Night Light options are grayed out in the Settings app. Colors become more warm and the backlight will be dimmed, so eye fatigue will be less.
When enabled, it makes the screen color gamma more comfortable for your eyes at night by reducing blue light. Windows 10 allows you to enable Night Light mode (previously known as Blue Light) to reduce eye strain. RECOMMENDED: Click here to fix Windows issues and optimize system performance